From LeFaye's notes in the appendices of the letters:

There were several branches of the Chamberlayne family in Oxfordshire, Warwickshire, and Gloucestershire; the latter family were distant cousins of Mrs GA by virtue of their common ancestor James Brydges, Lord Chandos of Sudeley (died 1714). In 1801 JA met in Bath Mr Edmund-John Chamberlayne (1766- 1831) of Maugersbury House, Glos., and his wife Cecil Talbot (1768-18)2), who were childless; and in 1805 in Bath she met Adm. Charles Chamberlayne (uncle of Mr EJC, died 1810) of Plymouth, with his wife Margaret and ten children; of these children she mentions Annabella (1787), Amelia (1789), Bickerton (1791), and Richard (1796). Bickerton may have been a godson of Sir Richard Bickerton, Port Admiral at Plymouth, who died 1792.

The Admiral's eldest sister, Lydia-Catherine (born 1737), married 1763 Laurence Irvine (q.v.), and had issue.

See R. Vick, 'Cousins in Bath', in JA Society Report for 1995, 24-9. Chambers. A former maidservant to Mrs Leigh-Perrot (p. 505).